The mean age was 5. A significant difference for factors like age and S. A binary logistic regression adjusted for genotypes, age and S. Dental caries is caused by a complex interaction between genetics and the environment [ 22 ].
Bacteria causes dental caries
Moreover, studies have found the link between dental caries and amelogenesis imperfecta. Some studies have clarified the genetic variation in AMELX linked with enamel formation contributed to caries susceptibility [ 3031 ]. Also, genetic variation in MMP and MMP was involved in increased caries risk during the enamel development [ 2832 ]. The VDR gene, identified as a candidate gene related to dental caries, mediated the biological function of the major metabolite of vitamin D, which was associated caries clasificacion enamel formation [ 89 ].
Vitamin D regulates the metabolism of calcium and promotes calcium depositing onto the enamel. Purvis et al. However, the molecular mechanisms of deciduous tooth decay regulated by the VDR gene were not certain. Valdivielso et al. VDR protein mediated the biological function of Vitamin D, via interaction with the Vitamin D, which was associated with dental caries [ 91015 ].
These results were inconsistent with previous study performed by Hu et al. According to studies conducted by Bayram M et al. Thus, the inconsistency between our results and other reported study may be caused by difference between the primary and permanent dentitions. Cogulu et al.
The limitation of this study was that we only investigated the relationship between VDR polymorphisms and caries risk of children in Guangzhou, China; however, dental caries was caused by multiple genetic factors and environment.
The mechanism of the possible effect of VDR on susceptibility to dental caries remained unclear, further research in people with different ethnic backgrounds should be performed to reveal the mechanism of VDR gene in caries incidence, and clarify its interactions with other susceptibility genes and environmental factors. YY Kong wrote the first draft of the manuscript. JM Zheng wrote the final draft of the manuscript. QZ Jiang contributed to obtaining the funding, and was responsible for experimental design, data collection and analysis.
All authors critically reviewed the final side effects from botox injections in neck of the manuscript. All authors read and approved the final manuscript. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. National Center for Biotechnology InformationU. BMC Oral Health. Published online Jul Author information Article notes Copyright and License information Disclaimer.
Corresponding author. Received Nov 10; Accepted Jun This article has been cited by other articles in PMC. Associated Data Data Availability Statement The data and materials of the present study were available from the corresponding author. Keywords: Deciduous tooth decay, Vitamin D receptor, Gene polymorphisms.
Results A total of children recruited in this study, Open in a separate window. Table 3 Binary logistic regression analysis adjusted for genotypes, age and S. Discussion Dental caries is caused by a complex interaction between genetics and the environment [ 22 ].
Availability of data and materials The data and materials of the present study were available from the corresponding author. Consent for publication Not applicable. Competing interests The authors declare that they have no competing interests.
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O que é uma carie dentaria
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Front Immunol. Slotwinska SM, Slotwinski R. Host response, malnutrition and oral diseases. Part 1. Indeed, their regular intake seems to decrease the salivary concentrations of S. Moreover, the daily consumption of probiotics leads to a significant reduction in caries, with more effect on the early lesions than on the cavity lesions. These promising results suggest that probiotics have a protective effect on our teeth! Short-term consumption of probiotic-containing cheese and its effect on dental caries risk factors.
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